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Novel yeast killer toxins provoke S-phase arrest and DNA damage checkpoint activation

โœ Scribed by Roland Klassen; Sabine Teichert; Friedhelm Meinhardt


Book ID
110832062
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
201 KB
Volume
53
Category
Article
ISSN
0950-382X

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## Abstract We have studied the rate of DNA synthesis, cell cycle distribution, formation of ฮณโ€H2AX, and Rad51 nuclear foci and association of Rad51 with the nuclear matrix after treatment of HeLa cells with the interstrand crosslinking agent mitomycin C (MMC) in the presence of the kinase inhibito