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Novel Triterpenoids from Microtropis triflora with Antitumor Activities

✍ Scribed by Kui-Wu Wang; Hong Zhang; Yuan-Jiang Pan


Publisher
John Wiley and Sons
Year
2007
Tongue
German
Weight
67 KB
Volume
90
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Two unprecedented norfriedelane‐type triterpenoids, triflora lactone (1) and triptocalline B (2), were isolated from the MeOH extract of the stalks of Microtropis triflora Merr. et Freem., together with five known compounds (37). Their structures were elucidated on the basis of spectroscopic and mass‐spectrometric data (Tables 1 and 2). The new compounds were found to be cytotoxic against human cervical squamous carcinoma (Hela) cells, with IC~50~ values of 21.6 and 17.6 μg/ml, respectively.


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