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Novel Synthesis of some Spiro Heterocycles Derived from 3-Hydroxy-3(2-Oxocyclohexyl)-Indolin-2-One

โœ Scribed by Abdel-Ghany, H.; Khodairy, A.; Moustafa, H. M.


Book ID
115315629
Publisher
Taylor and Francis Group
Year
2000
Tongue
English
Weight
348 KB
Volume
30
Category
Article
ISSN
0039-7911

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โœ Marzoog S. Al-Thebeiti ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 534 KB

Indole-2,3-dione ivas treated with malonic acid in a mixture of-ethanol/p?v-idine to afford I - [3-(2-oxoindoliii?.lideiiej]acetic acid (31, ivhich was theta reacted with thionFl chloride to give the corresponding acid chloride (4). The acid chloride 4 reacted with arenes in the presence of AlC1, to