✦ LIBER ✦

Novel synthesis of l-iduronic acid using trehalose as the disaccharidic starting material

✍ Scribed by Hiroshi Hinou; Hidehiro Kurosawa; Koji Matsuoka; Daiyo Terunuma; Hiroyoshi Kuzuhara

Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 255 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)02662-8

No coin nor oath required. For personal study only.

✦ Synopsis

For the preparation of L-iduronic acid, trehalose was converted into a derivative of a novel disaccharide, B-Lidopyranosyl I~-L-idopyranoside, through diastereoselective hydroboration of the 5, 5'-di-eno intermediate. The 6-and 6'-hydroxy groups were then oxidized in two steps to give a disaccharide composed of 2 units of Liduronate moieties, which underwent acidic cleavage of the glycosidic bond to give the target compound.

📜 SIMILAR VOLUMES

Parallel Synthesis of Arrays of Amino-Ac

Parallel Synthesis of Arrays of Amino-Acid-Derived Isocyanoamides Useful as Starting Materials in IMCR.

✍ Alexander Doemling; Barbara Beck; Thilo Fuchs; Ahmad Yazbak 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 26 KB

(S)-Pyroglutamic Acid, (S)-Malic Acid, a

(S)-Pyroglutamic Acid, (S)-Malic Acid, and (S)-Serine as Useful Starting Materials in the Synthesis of Enantiopure Hydroxyamidines

✍ Martin Ostendorf; Jan Dĳkink; Floris P. J. T. Rutjes; Henk Hiemstra 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 398 KB 👁 2 views

The synthesis of four enantiopure hydroxyamidines is amidine was obtained by coupling of an (S)-malic acid derived N-acyliminium ion with β-naphthol. The other described. One amidine was obtained from (S)-pyroglutamic acid. Its key step involved the addition of phenylmagnesium amidines were obtained

ChemInform Abstract: Synthesis, Reaction

ChemInform Abstract: Synthesis, Reactions, and Antiarrhythmic Activity of Substituted Heterocyclic Systems Using 5-Chloroanisic Acid as Starting Material.

✍ Ahmed F. A. Shalaby; Mohamed M. Abdulla; Abd El Galil E. Amr; Azza A. Hussain 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 40 KB 👁 2 views

ChemInform Abstract: Natural α-Amino Aci

ChemInform Abstract: Natural α-Amino Acids as Starting Materials for the Synthesis of Heterocycles

✍ Massimo Falorni; Andrea Porcheddu; Giampaolo Giacomelli 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: (S)-Pyroglutamic Ac

ChemInform Abstract: (S)-Pyroglutamic Acid, (S)-Malic Acid, and (S)-Serine as Useful Starting Materials in the Synthesis of Enantiopure Hydroxyamidines.

✍ Martin Ostendorf; Jan Dijkink; Floris P. J. T. Rutjes; Henk Hiemstra 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

The Synthesis of Novel Porous Functional

The Synthesis of Novel Porous Functional Materials for use as Nitrosamine Traps

✍ Y. Xu; Q. Jiang; Y. Cao; Y. L. Wei; Z. Y. Yun; J. H. Xu; Y. Wang; C. F. Zhou; L. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 558 KB