Novel synthesis of C-Nucleosides via radical coupling reaction
โ Scribed by Hideo Togo; Misa Fujii; Toshihiro Ikuma; Masataka Yokoyama
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 261 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
Photolysis of Oacyl-N-hydroxy-2-thiopyridone, derived from 2-tetrahydrofuryl carboxylic acid or 2,5anhydro-D-allonic acid, gave the corresponding Gnucleoside derivatives in the presence of heteroaromatic compounds via radical pathways.
๐ SIMILAR VOLUMES
We have shown that the configuration at the P-stereogenic centre in a range of H-phosphonates can be assigned using a combination of chromatographic mobility, 1 H and 31 P NMR data. We have also shown that the individual P-stereoisomers can be cross-coupled with vinyl and aryl halides, in the presen
A new synthesis of nucleoside analogues has been developed. The cyclocondensation of a glycosylated diazadiene or thiazadiene, with acyl chlorides or a-halogenoketones, respectively, resulted in good yields and excellent regioselectivities. We report an efficient method for the production of glucosy