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Novel Synthesis of Bis(phosphonic acid)−Steroid Conjugates

✍ Scribed by Page, Philip C. B.; McKenzie, Michael J.; Gallagher, James A.

Book ID
118276074
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
136 KB
Volume
66
Category
Article
ISSN
0022-3263

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## Abstract The __H__‐phosphonate bioconjugates of bile acids, conjugated with various alcohols and nucleosides, were obtained in one pot by a tandem transesterification with diphenyl phosphite (DPP). The synthesis of cholic acid derived phosphoramide from the corresponding __H__‐phosphonate was al