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Novel stilbenes isolated from the root bark of Ekebergia benguelensis

✍ Scribed by Daniel Chávez; Hee-Byung Chai; Tangai E. Chagwedera; Qi Gao; Norman R. Farnsworth; Geoffrey A. Cordell; John M. Pezzuto; A.Douglas Kinghorn

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
93 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

Four novel stilbenes (1-4) were isolated from the root bark of Ekebergia benguelensis. The structures were established by spectroscopic methods including 2D NMR analysis. The structure of 1, a new stilbene-coumarin hybrid representing a novel skeleton, was confirmed by single X-ray analysis. Compounds 1-4 were evaluated against a panel of human cancer cell lines.

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