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Novel Shikonin Derivatives Targeting Tubulin as Anticancer Agents

✍ Scribed by Guo, Jing; Chen, Xiao-Feng; Liu, Jing; Lin, Hong-Yan; Han, Hong-Wei; Liu, Hong-Chang; Huang, Shou-Cheng; Shahla, Baloch K.; Kulek, Andrew; Qi, Jin-Liang; Wang, Xiao-Ming; Ling, Li-Jun; Yang, Yong-Hua


Book ID
125332430
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
872 KB
Volume
84
Category
Article
ISSN
1747-0277

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## Abstract Microtubules are dynamic polymers that occur in eukaryotic cells and play important roles in cell division, motility, transport and signaling. They form during the process of polymerization of Ξ±- and Ξ²-tubulin dimers. Tubulin is a significant and heavily researched molecular target for