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Novel Routes to Chiral 2-Alkoxy-5-/6- methoxycarbonylmethylidenepyrrolidines/-piperidines

✍ Scribed by David, Olivier; Calvet, Sandrine; Chau, François; Vanucci-Bacqué, Corinne; Fargeau-Bellassoued, Marie-Claude; Lhommet, Gérard


Book ID
126029720
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
91 KB
Volume
69
Category
Article
ISSN
0022-3263

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6-Alkyl-and 6-(1-alkenyl)-5-iodo-2-pyrones, which are available as major products by reaction of the corresponding (Z)-2-en-4-ynoic acids with iodine and NaHCO 3 in CH 3 CN, undergo insertion of activated zinc metal into their carbon iodine bond to provide the corresponding 5-(iodozinc)-2-pyrones. H