Novel restriction fragment length polymorphism of the growth hormone gene in inbred rats
β Scribed by Tetsuo Kunieda; Hiroshi Ikadai; Minami Matsui; Nobuo Nomura; Tomonori Imamichi; Ryotaro Ishizaki
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 609 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0006-2928
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Two common Pst I and Taq I restriction enzyme fragment length polymorphisms (RFLPs) were detected at the human parathyroid hormone (PTH) gene locus. The allele frequencies in a Northern German population were 0.578/0.422 (Pst I) and 0.628/0.372 (Taq I). The allele distributions follow Hardy-Weinberg
Direct gene analysis of the haptoglobin gene region was carried out by Southern blotting using an Hp cDNA as probe. Two types of polymorphism were observed: one due to intragenic duplication, is characterized by a constant fragment length difference of 1700bp observed with several enzymes and by com