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Restriction fragment length polymorphisms at the human parathyroid hormone gene locus

✍ Scribed by Jörg Schmidtke; Bettina Pape; Ute Krengel; Ulrich Langenbeck; David N. Cooper; Erich Breyel; Hubert Mayer

Publisher
Springer
Year
1984
Tongue
English
Weight
369 KB
Volume
67
Category
Article
ISSN
0340-6717

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✦ Synopsis

Two common Pst I and Taq I restriction enzyme fragment length polymorphisms (RFLPs) were detected at the human parathyroid hormone (PTH) gene locus. The allele frequencies in a Northern German population were 0.578/0.422 (Pst I) and 0.628/0.372 (Taq I). The allele distributions follow Hardy-Weinberg expectations of equilibrium in the population. The Mendelian nature of the polymorphisms were confirmed in family studies.

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