reported the existence of an association between schizophrenia and homozygosity of a BUZZ polymorphism in the first exon of the dopamine D3 receptor (DRDS) gene. In response to this report, further studies were conducted; however, these studies yielded conflicting results. In the present study, we e
โฆ LIBER โฆ
Novel, Replicated Associations Between Dopamine D3 Receptor Gene Polymorphisms and Schizophrenia in Two Independent Samples
โ Scribed by Michael E. Talkowski; Hader Mansour; Kodavali V. Chowdari; Joel Wood; Allison Butler; Panchami G. Varma; Suman Prasad; Prachi Semwal; Triptish Bhatia; Smita Deshpande; Bernie Devlin; B.K. Thelma; Vishwajit L. Nimgaonkar
- Book ID
- 119197228
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 322 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0006-3223
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DNA fragments from a genomic library were used to establish the partial structure of the human dopamine D3 receptor gene (DRD3). Its coding sequence contains 6 exons and stretches over 40,000 base pairs. The complete DRD3 transcript and three shorter variants, in which the second andor third exon ar