𝔖 Bobbio Scriptorium
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Novel properties of a spirocyclic dienone related to the alkaloid, cularine.

✍ Scribed by A.H. Jackson; G.W. Stewart


Publisher
Elsevier Science
Year
1971
Tongue
French
Weight
156 KB
Volume
12
Category
Article
ISSN
0040-4039

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✦ Synopsis


Cularine

(2~) and related alkaloids may arise in nature via phenolic coupling


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A novel approach to the regioselective acylation of spirocyclic C-glucoside of papulacandins is reported. Conditions were found to effect regioselective acylation of triol 2 to give 2-O-acyl derivatives (5), which after deprotection with TASF afforded exclusively 2-O-acyl derivatives ( 8). An extens