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Novel Potent and Efficacious Nonpeptidic Urotensin II Receptor Agonists

✍ Scribed by Lehmann, Fredrik; Pettersen, Anna; Currier, Erika A.; Sherbukhin, Vladimir; Olsson, Roger; Hacksell, Uli; Luthman, Kristina

Book ID
127014570
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
179 KB
Volume
49
Category
Article
ISSN
0022-2623

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## Abstract Urotensin II (U‐II) has been known for over 30 years as an important teleost fish hormone, but only recently has it been recognized as the endogenous ligand of a new human G‐protein‐coupled receptor (GPCR) homologous to the GPR14 orphan receptor from rat. Human U‐II was found to be a po