Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
โ Scribed by Ames, Robert S.; Sarau, Henry M.; Chambers, Johathan K.; Willette, Robert N.; Aiyar, Nambi V.; Romanic, Anne M.; Louden, Calvert S.; Foley, James J.; Sauermelch, Charles F.; Coatney, Robert W.; Ao, Zhaohui; Disa, Jyoti; Holmes, Stephen D.; Stadel, Jeffrey M.; Martin, John D.; Liu, Wu-Schyong; Glover, George I.; Wilson, Shelagh; McNulty, Dean E.; Ellis, Catherine E.; Elshourbagy, Nabil A.; Shabon, Usman; Trill, John J.; Hay, Douglas W. P.; Ohlstein, Eliot H.; Bergsma, Derk J.; Douglas, Stephen A.
- Book ID
- 109820118
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 313 KB
- Volume
- 401
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/45809
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The orphan receptor, human bombesin receptor subtype 3 (BRS-3) was assigned to the G-protein coupled bombesin receptor family because of its high sequence homology with the neuromedin B receptor (NMB-R) and gastrin-releasing peptide receptor (GRP-R). Since its pharmacology is stiIl unknown, new high