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Novel polyamine derivatives as potent competitive inhibitors of Trypanosoma cruzi trypanothione reductase

✍ Scribed by Mary C. O'Sullivan; Qibing Zhou


Book ID
118415122
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
229 KB
Volume
5
Category
Article
ISSN
0960-894X

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ChemInform Abstract: New Potent Inhibito
✍ S. GIRAULT; S. BAILLET; D. HORVATH; V. LUCAS; E. DAVIOUD-CHARVET; A. TARTAR; C. πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 28 KB πŸ‘ 2 views

New Potent Inhibitors of Trypanothione Reductase from Trypanosoma cruzi in the 2-Aminodiphenylsulfide Series. -A series of compounds such as (I)-(III) are prepared to investigate their TR inhibition. Derivative (Ib) is revealed to be the best inhibitor described so far.