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ChemInform Abstract: New Potent Inhibitors of Trypanothione Reductase from Trypanosoma cruzi in the 2-Aminodiphenylsulfide Series.

✍ Scribed by S. GIRAULT; S. BAILLET; D. HORVATH; V. LUCAS; E. DAVIOUD-CHARVET; A. TARTAR; C. SERGHERAERT

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199725245

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✦ Synopsis

New Potent Inhibitors of Trypanothione Reductase from Trypanosoma cruzi in the 2-Aminodiphenylsulfide Series.

-A series of compounds such as (I)-(III) are prepared to investigate their TR inhibition. Derivative (Ib) is revealed to be the best inhibitor described so far.

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