ChemInform Abstract: A General Approach to the Synthesis of Polyamine Linked-Monoindolylmaleimides, a New Series of Trypanothione Reductase Inhibitors.
β Scribed by L. SALMON; V. LANDRY; O. MELNYK; L. MAES; C. SERGHERAERT; E. DAVIOUD-CHARVET
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
New Potent Inhibitors of Trypanothione Reductase from Trypanosoma cruzi in the 2-Aminodiphenylsulfide Series. -A series of compounds such as (I)-(III) are prepared to investigate their TR inhibition. Derivative (Ib) is revealed to be the best inhibitor described so far.
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