Novel planar chiral phosphite: Preparation and use in the synthesis of Pd(II) complexes and in Pd-catalyzed allylic alkylation
β Scribed by V. N. Tsarev; S. I. Konkin; N. M. Loim; E. S. Kelbysheva; L. N. Popova; P. V. Petrovskii; V. A. Davankov; K. N. Gavrilov
- Book ID
- 111458076
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2007
- Tongue
- English
- Weight
- 199 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1070-3284
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Some novel ferrocenylphosphine-amidine ligands with central and planar chirality were prepared from (R,S p )-PPFNH 2 -R 3 and its diastereomer (S,S p )-PPFNH 2 3a. The efficiency and diastereomeric impact of these ferrocenylphosphine-amidine ligands in the palladium-catalyzed asymmetric allylic subs
A family of novel ferrocenylphosphine-amidine ligands derived from (R)-(S)-PPFNH 2 -R 5 was applied to the palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenylprop-2-en-1-yl acetate 8a or pivalate 8b with dimethyl malonate. Up to 94% e.e. was achieved when ligand 6b was used.