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Novel Peptidyl α-Keto Amide Inhibitors of Calpains and Other Cysteine Proteases

✍ Scribed by Li, Zhaozhao; Ortega-Vilain, Anne-Cécile; Patil, Girish S.; Chu, Der-Lun; Foreman, J. E.; Eveleth, David D.; Powers, James C.


Book ID
120604713
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
267 KB
Volume
39
Category
Article
ISSN
0022-2623

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Peptidyl α-keto amide inhibitor of calpa
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## Abstract The cysteine protease calpain is activated by calcium and has a wide range of substrates. Calpain‐mediated cellular damage is associated with many neuropathologies, and calpain also plays a role in signal transduction events that are essential for cell maintenance, including the activat