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Novel Functions of Human α1-Protease Inhibitor after S-Nitrosylation: Inhibition of Cysteine Protease and Antibacterial Activity

✍ Scribed by Yoichi Miyamoto; Takaaki Akaike; M.Samiul Alam; Katsuhisa Inoue; Takayoshi Hamamoto; Norisato Ikebe; Jun Yoshitake; Tatsuya Okamoto; Hiroshi Maeda


Book ID
115585136
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
148 KB
Volume
267
Category
Article
ISSN
0006-291X

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## Abstract Human plasminogen activator inhibitor type 1 (PAI‐1) is a serine protease inhibitor with a metastable active conformation. Under physiological conditions, half of the inhibitor transitions to a latent state within 1–2 h. The interaction between PAI‐1 and the plasma protein vitronectin p