Novel One-Pot, Four-Component Condensation Reaction: An Efficient Approach for the Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazole Derivatives by a Ugi-4CR/aza-Wittig Sequence
โ Scribed by Ramazani, Ali; Rezaei, Aram
- Book ID
- 115516198
- Publisher
- American Chemical Society
- Year
- 2010
- Tongue
- English
- Weight
- 217 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1523-7060
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๐ SIMILAR VOLUMES
## Abstract Reactions of (__N__โisocyanimino) triphenylphosphorane with 2โoxopropylbenzoate (or acetate) in the presence of aromatic carboxylic acids and primary amines proceed smoothly at room temperature and in neutral conditions to afford sterically congested 1,3,4โoxadiazole derivatives in high
## Abstract The multicomponent reaction between oxopropylbenzoate(acetate) (I), (VI), primary amines (II), (Nโisocyanimino)triphenylphosphorane (III), and aromatic carboxylic acids (IV) proceeds smoothly at room temperature under neutral conditions to afford the sterically congested oxadiazole deri