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ChemInform Abstract: A One-Pot Efficient Four-Component Reaction for the Synthesis of 2-(Arylamino)-2-(5-aryl-1,3,4-oxadiazol-2-yl)propyl Benzoate (or Acetate) Derivatives.

✍ Scribed by Ali Ramazani; Yavar Ahmadi; Asemeh Mashhadi Malekzadeh; Aram Rezaei

Publisher: John Wiley and Sons
Year: 2012
Weight: 15 KB
Volume: 43
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201210137

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✦ Synopsis

Abstract

The multicomponent reaction between oxopropylbenzoate(acetate) (I), (VI), primary amines (II), (N‐isocyanimino)triphenylphosphorane (III), and aromatic carboxylic acids (IV) proceeds smoothly at room temperature under neutral conditions to afford the sterically congested oxadiazole derivatives (V) and (VII), resp.

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