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Novel N -Aryl and N -Heteroaryl Sulfamide Synthesis via Palladium Cross Coupling

โœ Scribed by Alcaraz, Lilian; Bennion, Colin; Morris, James; Meghani, Premji; Thom, Stephen M.


Book ID
125543920
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
108 KB
Volume
6
Category
Article
ISSN
1523-7060

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Synthesis of chiral N-aryl pyrrolidinone
โœ R.Greg Browning; Hossen Mahmud; Vivek Badarinarayana; Carl J Lovely ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 62 KB

The direct synthesis of non-racemic N-aryl pyrrolidinones through the application of the Buchwald/Hartwig aryl amination reaction is reported. These reactions proceed in generally good yield, with a variety of electron deficient aryl bromides and with retention of stereochemical purity.