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Novel mutations of the APC gene in familial adenomatous polyposis in Greek patients

โœ Scribed by M Mihalatos; I Danielides; J Belogianni; E Harokopos; E Papadopoulou; G Kalimanis; M Tsiava; J.K Triantafillidis; P.A Kosmidis; G Fountzilas; G Basdanis; N.J Agnantis; D Yannoukakos; G Nasioulas

Book ID
114135492
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
161 KB
Volume
141
Category
Article
ISSN
0165-4608

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๐Ÿ“œ SIMILAR VOLUMES

Characterization of two novel adenomatou
Characterization of two novel adenomatous polyposis coli (APC) gene mutations in patients with familial adenomatous polyposis (FAP)
โœ Bharati Bapat; Terri Berk; Angela Mitri; Zane Cohen; Steven Gallinger; Hartley S ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 398 KB ๐Ÿ‘ 2 views

Patients with Familial Adenomatous Polyposis (FAP) manifest numerous colorectal adenomas as well as benign and malignant extra-colonic lesions. Adenomatous polyposis coli (APC) gene mutations are the underlying genetic defect in FAP. We analyzed germline D N A of 81 unrelated FAP patients and evalua

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Familial adenomatous polyposis coli: Five novel mutations in exon 15 of the adenomatous polyposis coli (APC) gene in Italian patients
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## Germline mutations within the adenomatous polyposis coli (APC ) gene, a tumor suppressor gene, are responsible for most cases of familial adenomatous polyposis (FAP), an autosomal dominantly inherited predisposition to colorectal cancer. To date, more than 300 germ-line causative mutations with