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Novel Method for Synthesis of 2-Aryl-2,3,7,8-tetrahydro-4H,6H-pyrimido[2,1-b]-1,3-thiazin-4-ones Hydrochlorides

✍ Scribed by V.N. Britsun; M.O. Lozinskii

Book ID: 110305011
Publisher: Springer US
Year: 2001
Tongue: English
Weight: 99 KB
Volume: 37
Category: Article
ISSN: 0009-3122
DOI: 10.1023/a:1011902421033

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ChemInform Abstract: Novel Method for Sy

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## Abstract The reaction of 1‐aryl‐3‐(dimethylamino)‐1‐propanones 1 with one equivalent of 4,5‐diamino‐1__H__‐pyrimidin‐6‐ones 2, in acidic medium, leads to the formation of 4‐aryl‐2,3,6,7‐tetrahydro‐1__H__‐pyrimido[4,5‐__b__]‐[1,4]diazepin‐6‐ones 3. The structure elucidation of the products is bas