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Novel Genes Mapping to the Critical Region of the 5q− Syndrome

✍ Scribed by Jacqueline Boultwood; Carrie Fidler; Pascal Soularue; Amanda J. Strickson; Markus Kostrzewa; Rina J. Jaju; Finbarr E. Cotter; Nick Fairweather; Anthony P. Monaco; Ulrich Müller; Michael Lovett; Ethylin Wang Jabs; Charles Auffray; James S. Wainscoat


Book ID
115613973
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
198 KB
Volume
45
Category
Article
ISSN
0888-7543

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The 5qϪ syndrome is a distinct type of myelodysplastic syndrome (MDS) characterised by refractory anaemia, morphological abnormalities of megakaryocytes, and del(5q) as the sole cytogenetic abnormality. In contrast to patients with therapy-related MDS with 5q deletions, 5qϪ syndrome patients have a