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Molecular Mapping of Uncharacteristically Small 5q Deletions in Two Patients with the 5q- Syndrome: Delineation of the Critical Region on 5q and Identification of a 5q- Breakpoint

✍ Scribed by J. Boultwood; C. Fidler; S. Lewis; S. Kelly; H. Sheridan; T.J. Littlewood; V.J. Buckle; J.S. Wainscoat


Book ID
115611957
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
561 KB
Volume
19
Category
Article
ISSN
0888-7543

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The 5qΟͺ syndrome is a distinct type of myelodysplastic syndrome (MDS) characterised by refractory anaemia, morphological abnormalities of megakaryocytes, and del(5q) as the sole cytogenetic abnormality. In contrast to patients with therapy-related MDS with 5q deletions, 5qΟͺ syndrome patients have a