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Novel furo[2,3-d] pyrimidine derivative as fluorescent chemosensor for HSO4−

✍ Scribed by Weijian Xue; Lin Li; Qi Li; Anxin Wu


Book ID
116905586
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
645 KB
Volume
88
Category
Article
ISSN
0039-9140

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## Abstract Receptor tyrosine kinases such as VEGFR2 (vascular endothelial growth factor receptor 2, KDR) or EGFR (epidermal growth factor receptor) play crucial roles in a variety of diseases, such as cancer. Recently, some pyrrolopyrimidines were shown to be potent EGFR inhibitors. Therefore, new