✦ LIBER ✦

Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors

✍ Scribed by Yasushi Miyazaki; Shinichiro Matsunaga; Jun Tang; Yutaka Maeda; Masato Nakano; Rocher J. Philippe; Megumi Shibahara; Wei Liu; Hideyuki Sato; Liping Wang; Robert T. Nolte

Book ID: 108073617
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 177 KB
Volume: 15
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2005.03.034

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Novel 4-Amino-furo[2,3-d]pyrimidines as

Novel 4-Amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 Dual Inhibitors.

✍ Yasushi Miyazaki; et al. et al. 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 20 KB 👁 1 views

Orally Active 4-Amino-5-diarylurea-furo[

Orally Active 4-Amino-5-diarylurea-furo[2,3-d]pyrimidine Derivatives as Antiangiogenic Agent Inhibiting VEGFR2 and Tie-2.

✍ Yasushi Miyazaki; et al. et al. 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 21 KB 👁 1 views

Orally active 4-amino-5-diarylurea-furo[

Orally active 4-amino-5-diarylurea-furo[2,3-d]pyrimidine derivatives as anti-angiogenic agent inhibiting VEGFR2 and Tie-2

✍ Yasushi Miyazaki; Jun Tang; Yutaka Maeda; Masato Nakano; Liping Wang; Robert T. 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 251 KB

Furo[2,3-d]pyrimidines and Oxazolo[5,4-d

Furo[2,3-d]pyrimidines and Oxazolo[5,4-d]pyrimidines as Inhibitors of Receptor Tyrosine Kinases (RTK)

✍ Andreas Martin-Kohler; Jörg Widmer; Guido Bold; Thomas Meyer; Urs Séquin; Peter 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 276 KB 👁 1 views

## Abstract Receptor tyrosine kinases such as VEGFR2 (vascular endothelial growth factor receptor 2, KDR) or EGFR (epidermal growth factor receptor) play crucial roles in a variety of diseases, such as cancer. Recently, some pyrrolopyrimidines were shown to be potent EGFR inhibitors. Therefore, new

Novel furo[2,3-d] pyrimidine derivative

Novel furo[2,3-d] pyrimidine derivative as fluorescent chemosensor for HSO4−

✍ Weijian Xue; Lin Li; Qi Li; Anxin Wu 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 645 KB

2-Diisopropylamino-3-phenylbenzo[4,5]f

2-Diisopropylamino-3-phenylbenzo[4,5]furo[3,2-d]pyrimidin-4(3H)-one

✍ Hu, Yang-Gen ;Xu, Sheng-Zhen ;Yuan, Ju-Zhen ;Ding, Ming-Wu ;He, Hong-Wu 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 351 KB

In the title compound, C 22 H 23 N 3 O 2 , the three fused rings of the benzofuro[3,2-d]pyrimidine system are almost coplanar. The packing of the molecules in the crystal structure is mainly due toand intermolecular C-HÁ Á ÁO hydrogen-bonding interactions.