Novel formation of 6-acyl-5-(2-pyrrolyl)-3H-pyrrolizines by base-catalysed condensation of pyrrole-2-aldehyde with methyl ketones

✍ Scribed by Asok K. Mallik; Sankar P. Dey; Falguni Chattopadhyay; Amarendra Patra

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 241 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)02284-5

✦ Synopsis

Pyrrole-2-aldehyde undergoes condensation with methyl ketones in aqueous ethanolic alkali in a 2:1 mole ratio yielding 6-acyl-5-(2-pyrrolyl)-3H-pyrrolizines as novel products in moderate yield.