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ChemInform Abstract: Novel Formation of 6-Acyl-5-(2-pyrrolyl)-3H-pyrrolizines by Base-Catalyzed Condensation of Pyrrole-2-aldehyde with Methyl Ketones.

โœ Scribed by Asok K. Mallik; Sankar P. Dey; Falguni Chattopadhyay; Amarendra Patra


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
33
Category
Article
ISSN
0931-7597

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Novel formation of 6-acyl-5-(2-pyrrolyl)
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Pyrrole-2-aldehyde undergoes condensation with methyl ketones in aqueous ethanolic alkali in a 2:1 mole ratio yielding 6-acyl-5-(2-pyrrolyl)-3H-pyrrolizines as novel products in moderate yield.

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## Abstract A reaction mechanism with in situ generated HCl as primary promoter is proposed.