Novel enantioselective synthesis of (2S,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)glycine (DCG-IV)
✍ Scribed by Maura Marinozzi; Roberto Pellicciari
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 68 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
A novel enantioselective synthesis of (2S,2%R,3%R)-2-(2%,3%-dicarboxycyclopropyl)glycine (DCG-IV), a potent group II mGluRs agonist is described.
📜 SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
New conformationally restricted glutamate analogues 2-(3'-alkyl-2'-carboxycyclopropyl)glycines (la-e and 2a-e) were enantioselectively prepared by the addition-elimination reaction of the chiral lithium bislactim ether anion of 3 to racemic 4-alkyl-4-bromobut-2-enoates.