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Novel Domino Reactions of ( Z , Z )-2,2′-Thiobis(1,3-diarylprop-2-en-1-ones) with Acetylacetone and Ethyl Acetoacetate: Stereoselective Synthesis of Highly Functionalized Dihydrofurans

✍ Scribed by Vinosha, Beer Mohamed; Renuga, Subbiah; Gnanadeebam, Michael; Perumal, Subbu; Lycka, Antonin


Book ID
118154370
Publisher
Taylor and Francis Group
Year
2009
Tongue
English
Weight
296 KB
Volume
39
Category
Article
ISSN
0039-7911

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Highly efficient and stereoselective acc
✍ Kazumasa Funabiki; Yoshitaka Fukushima; Tomomi Inagaki; Eiji Murata; Masaki Mats 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 254 KB

2,3,3-Trifluoro-l-pmpenyl p-chlorobenzenesulfonate (1), readily available from 2,2,3,3tetrafluoropmpanol, reacted smoothly with various Grignard reagents at 50 °(3 to afford the corresponding (Z)-a, fl-difluoroallyl alcohols 2 in moderate to excellent yields. These alcohols were smoothly hydrolyzed