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Novel constitutional t(2;12)(q21;q22) in a patient with t(9;22)-negative chronic myelocytic leukemia

✍ Scribed by Alwin Krämer; Stefan Fruehauf; Anthony D. Ho; Hans-Dieter Hager; Claus R. Bartram; Andreas Hochhaus


Book ID
114135521
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
186 KB
Volume
142
Category
Article
ISSN
0165-4608

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A 46-year-old man with chronic myelocytic leukemia had a new variant translocation between chromosome 22 and chromosome 7 in bone marrow cells. No involvement of chromosome 9 was seen. The patient entered blastic transformation within half a year, by which time he had acquired an isochromosome 17 in