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A t(20;21)(q12;q22.3) in a patient with chronic myelocytic leukemia in blastic phase

✍ Scribed by Alessandro Gozzetti; Daniela Tozzuoli; Rosaria Crupi; Sara Gentili; Donatella Raspadori; Alberto Fabbri; Francesco Lauria


Book ID
113512309
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
171 KB
Volume
150
Category
Article
ISSN
0165-4608

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A 46-year-old man with chronic myelocytic leukemia had a new variant translocation between chromosome 22 and chromosome 7 in bone marrow cells. No involvement of chromosome 9 was seen. The patient entered blastic transformation within half a year, by which time he had acquired an isochromosome 17 in