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Novel carbocyclic nucleosides related to oxetanocin

✍ Scribed by Johnson, Carl R.; De Jong, Randall L.

Book ID
120387501
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
852 KB
Volume
57
Category
Article
ISSN
0022-3263

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Modified oligonucleotides, hexadecamers, containing carbocyclic analogues of oxetanocin A and T, have been synthesized from the corresponding chiral carbocyclic nucleosides. The oligonucleotide derived from carbocyclic oxetanocin A forms a stable triple-helix with uridine oligoribonucleotide even un