𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Novel cAMP PDE III inhibitors: 1,6-naphthyridin-2(1H)-ones

✍ Scribed by Singh, Baldev; Lesher, George Y.; Pluncket, Kevin C.; Pagani, Edward D.; Bode, Donald C.; Bentley, Ross G.; Connell, Mary J.; Hamel, Linda T.; Silver, Paul J.


Book ID
111898030
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
871 KB
Volume
35
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Synthesis of Substituted 1,2-Dihydro-2-i
✍ Ivanov, Ivo Christov ;Stoyanov, Edmont Vassilev ;Denkova, Pavletta Stoyanova ;Di πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 470 KB

## Abstract Vilsmeier formylation of the 4‐amino‐2‐pyridinones 4a–d leads to the formation of the corresponding 3‐carbaldehydes 5a–d (the diformylated product 8 is isolated as a by‐product). A cyclizing Knoevenagel reaction of 5 with CH‐acidic nitriles 6 in the presence of piperidine gives substitu