✦ LIBER ✦

Novel Bradykinin Analogues Modified in the N-Terminal Part of the Molecule with a Variety of Acyl Substituents

✍ Scribed by Małgorzata Śleszyńska, Tomasz H. Wierzba, Krzysztof Malinowski, Tereza Tůmová, Bernard Lammek, Jiřina Slaninová, Adam Prahl

Book ID: 113073815
Publisher: Springer Netherlands
Year: 2012
Tongue: English
Weight: 233 KB
Volume: 18
Category: Article
ISSN: 1573-3149
DOI: 10.1007/s10989-011-9285-5

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Novel analogues of bradykinin conformati

Novel analogues of bradykinin conformationally restricted in the C-terminal part of the molecule

✍ Małgorzata Śleszyńska; Tomasz H. Wierzba; Krzysztof Malinowski; Lenka Borovičkov 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB

## Abstract In the present work, achiral non‐coded amino acids, N‐(Bzl)‐Gly, X~1~ or X~2~, were substituted at position 7 of the model B~2~ receptor antagonist [D‐Arg^0^, Hyp^3^, Thi^5, 8^, D‐Phe^7^]‐BK. The N‐terminal amino group of the analogues was either free or acylated with 1‐Aca or Aaa. Biol

Analogues of arginine vasopressin modifi

Analogues of arginine vasopressin modified in the N-terminal part of the molecule with enantiomers of N-methylphenylalanine

✍ Kowalczyk, W. ;Derdowska, I. ;Dawidowska, O. ;Prahl, A. ;Hartrodt, B. ;Neubert, 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 101 KB

Analogues of AVP modified in the N-termi

Analogues of AVP modified in the N-terminal part of the molecule with Pip isomers: TFA-catalysed peptide bond hydrolysis

✍ Dariusz Sobolewski; Adam Prahl; Anna Kwiatkowska; Jiřina Slaninová; Bernard Lamm 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB

## Abstract Using SPPS techniques, six new analogues of AVP and some of its agonists were synthesised. The peptides were designed by substitution of Phe at position 3 of AVP, [Mpa^1^] AVP (dAVP) and [Mpa^1^,Val^4^,D‐Arg^8^]VP (dVDAVP) with L‐ or D‐Pip, a non‐coded α‐imino acid, also called homoprol

Analogues of arginine vasopressin and it

Analogues of arginine vasopressin and its agonist and antagonist modified in the N-terminal part of the molecule with l-beta-homophenylalanine

✍ Sobolewski, D. ;Kowalczyk, W. ;Prahl, A. ;Derdowska, I. ;Slaninova, J. ;Zabrocki 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 116 KB

Analogues of Neurohypophyseal Hormones,

Analogues of Neurohypophyseal Hormones, Oxytocin and Arginine Vasopressin, Conformationally Restricted in the N-Terminal Part of the Molecule

✍ Kowalczyk, Wioleta; Prahl, Adam; Derdowska, Izabela; Sobolewski, Dariusz; Olejni 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 60 KB

Analogs of arginine vasopressin modified

Analogs of arginine vasopressin modified in the N-terminal part of the molecule with a conformationally constrained cis-peptide bond motif

✍ Dariusz Sobolewski; Adam Prahl; Izabela Derdowska; Jiřina Slaninová; Krzysztof K 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 124 KB

## Abstract The present work is part of our studies aimed at clarifying the influence of steric constraints in the __N__‐terminal part of arginine vasopressin (AVP) and its analogs on the pharmacological activity of the resulting peptides. We describe the synthesis of eight new analogs of AVP or [3