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Analogues of arginine vasopressin and its agonist and antagonist modified in the N-terminal part of the molecule with l-beta-homophenylalanine

✍ Scribed by Sobolewski, D. ;Kowalczyk, W. ;Prahl, A. ;Derdowska, I. ;Slaninova, J. ;Zabrocki, J. ;Lammek, B.


Book ID
110893858
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
116 KB
Volume
65
Category
Article
ISSN
1397-002X

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📜 SIMILAR VOLUMES


Analogs of arginine vasopressin modified
✍ Dariusz Sobolewski; Adam Prahl; Izabela Derdowska; Jiřina Slaninová; Krzysztof K 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 124 KB

## Abstract The present work is part of our studies aimed at clarifying the influence of steric constraints in the __N__‐terminal part of arginine vasopressin (AVP) and its analogs on the pharmacological activity of the resulting peptides. We describe the synthesis of eight new analogs of AVP or [3

Analogues of AVP modified in the N-termi
✍ Dariusz Sobolewski; Adam Prahl; Anna Kwiatkowska; Jiřina Slaninová; Bernard Lamm 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB

## Abstract Using SPPS techniques, six new analogues of AVP and some of its agonists were synthesised. The peptides were designed by substitution of Phe at position 3 of AVP, [Mpa^1^] AVP (dAVP) and [Mpa^1^,Val^4^,D‐Arg^8^]VP (dVDAVP) with L‐ or D‐Pip, a non‐coded α‐imino acid, also called homoprol