Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester
✍ Scribed by Maria José Alves; Paula M.T Ferreira; Hernâni L.S Maia; Luı́s S Monteiro; Thomas L Gilchrist *
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 208 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate acts as an ecient alkylating agent for a variety of ®ve-membered aromatic heterocycles. The aziridines derived from heterocycles that bear an a-carbonyl substituent react with TFA to give pyrroloimidazoles; 2,6-dichlorobenzaldehyde is also produced.
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