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Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester

✍ Scribed by Maria José Alves; Paula M.T Ferreira; Hernâni L.S Maia; Luı́s S Monteiro; Thomas L Gilchrist *


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
208 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis


Methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate acts as an ecient alkylating agent for a variety of ®ve-membered aromatic heterocycles. The aziridines derived from heterocycles that bear an a-carbonyl substituent react with TFA to give pyrroloimidazoles; 2,6-dichlorobenzaldehyde is also produced.


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