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Novel antitumour metabolites produced by a fungal strain from a sea hare

✍ Scribed by Atsushi Numata; Masashi Iritani; Takeshi Yamada; Katsuhiko Minoura; Eiko Matsumura; Takao Yamori; Takashi Tsuruo

Book ID
104258271
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
248 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

Pericosines A (1) and B (2), and macrosphelides E -H (3 -6)have bccn isolated, alongwith known macrosphelide C (7), from a strain ofPericonia byssoides originally scpiratcd from the sea h~ Aplysia /aa'odai, and their stmc~ur~ have been Β’stablish~ on the basis of spectral ~,mlyses. Compounds I and 2 exhibited significant inhibitory activity in vitro against turnout cells, and the former also showed significant in vivo turnout-inhibitory activity.

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