Gymnastatins, novel cytotoxic metabolites produced by a fungal strain from a sponge
β Scribed by Atsushi Numata; Taro Amagata; Katsuhiko Minoura; Tadayoshi Ito
- Book ID
- 104257590
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 214 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Gymnastatins A-C, produced by a strain ofGymnasella dankaliensis ~'om the sponge Halichondriajaponica, are novel compounds with significant cytotoxicity against tumour cells in culture.
Their stereostrucmres have been established on the basis of spectral analyses.
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Pericosines A (1) and B (2), and macrosphelides E -H (3 -6)have bccn isolated, alongwith known macrosphelide C (7), from a strain ofPericonia byssoides originally scpiratcd from the sea h~ Aplysia /aa'odai, and their stmc~ur~ have been Β’stablish~ on the basis of spectral ~,mlyses. Compounds I and 2