𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Novel anticancer therapeutics targeting telomerase

✍ Scribed by Ruden, Maria; Puri, Neelu


Book ID
118118160
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
973 KB
Volume
39
Category
Article
ISSN
0305-7372

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Histone deacetylase inhibition as an ant
✍ Ruman Rahman; Richard Grundy πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 French βš– 556 KB

## Abstract Aberrant epigenetic regulation of gene expression contributes to tumor initiation and progression. Studies from a plethora of hematologic and solid tumors support the use of histone deacetylase inhibitors (HDACi) as potent anticancer agents. The mechanism(s) of HDACi‐induced cancer grow

Telomerase as a possible target for anti
✍ Chantal Autexier πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 68 KB

Telomeres, the termini of chromosomes, provide essential stability to linear eukaryotic chromosomes. The enzyme telomerase is one mechanism that maintains telomeres, and is activated in 85% of human cancer cells. New studies on peptide nucleic acids (PNAs) that inhibit telomerase have demonstrated t