Novel and selective synthesis of unsymmetrical azine derivatives via a mild reaction
✍ Scribed by Safari, Javad; Gandomi-Ravandi, Soheila; Monemi, Mohammad
- Book ID
- 120252051
- Publisher
- Springer Vienna
- Year
- 2013
- Tongue
- English
- Weight
- 272 KB
- Volume
- 144
- Category
- Article
- ISSN
- 0026-9247
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The diazonium salt of 2‐aminophenol **2** was coupled __in situ__ with malononitrile derivatives **3a‐d**, 2‐cyanomethylthiazolin‐4‐one **9**, 2‐cyanomethylbenzimidazole **11a**, and 2‐cyanomethylbenzothiazole **11b** to give 2‐amino[1,4,5]benzoxadiazepine derivatives **6a‐d, 10** and *
Treatment of cis-1-iodo-3-chloro-1-propene derivatives, readily obtainable via trans addition of organometals to propargyl alcohols followed by iodinolysis and chlorination, with alkyllithiums, such as t-BuLi and n-BuLi, can proceed rapidly and cleanly even at -78°C to give in high yields cycloprope