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Novel and practical asymmetric synthesis of an azetidine alkaloid, penaresidin B

✍ Scribed by Hidemi Yoda; Takuya Uemura; Kunihiko Takabe

Book ID: 104252824
Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 92 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)02743-0

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✦ Synopsis

A novel and efficient asymmetric synthesis of the potent actomyosin ATPase activator, penaresidin B, is described in a short and complete stereoselective manner by featuring the elaboration of the fully functionalized homochiral lactam, which can also be regarded as an advanced intermediate for the synthesis of other azetidine alkaloids.

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