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Novel aldose reductase inhibitors: a patent survey (2006 – present)

✍ Scribed by Chatzopoulou, Maria; Alexiou, Polyxeni; Kotsampasakou, Eleni; Demopoulos, Vassilis J

Book ID
120408625
Publisher
Informa plc
Year
2012
Tongue
English
Weight
734 KB
Volume
22
Category
Article
ISSN
1354-3776

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Structure and synthesis of WF 3681, a no
Structure and synthesis of WF 3681, a novel aldose reductase inhibitor
✍ Itsuo Uchida; Yoshikuni Itoh; Takayuki Namiki; Motoaki Nishikawa; Masashi Hashim 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 214 KB

The structure of WF 3681 (L), an aldose reductase inhibitor isolated from a ChaetomeIla species, has been determined on the basis of its physical and chemical properties and confirmed by a total synthesis. WF 3681 ( 1) is a fungal metabolite with potent aldose reductaseinhibitory activity. Herein we