ChemInform Abstract: Design and Synthesi
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R. GOESCHKE; N. C. COHEN; J. M. WOOD; J. MAIBAUM
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Article
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2010
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John Wiley and Sons
⚖ 31 KB
Design and Synthesis of Novel 2,7-Dialkyl Substituted 5(S)-Amino-4(S)-hydroxy-8-phenyl-octanecarboxamides as in vitro Potent Peptidomimetic Inhibitors of Human Renin. -Novel renin inhibitors (I), which are created on a topographical design approach, are prepared by literature methods. (I) have IC 50