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Novel 2,4-dianilino-5-fluoropyrimidine derivatives possessing ALK inhibitory activities

✍ Scribed by Yun, Jeong In; Yang, Eun Hye; Latif, Muhammad; Lee, Hyeon Ji; Lee, Kwangho; Yun, Chang-Soo; Park, Chi Hoon; Lee, Chong Ock; Chae, Chong Hak; Cho, Sung Yun; Jung, Hee Jung; Kim, Pilho; Choi, Sang Un; Kim, Hyoung Rae


Book ID
125380067
Publisher
Springer
Year
2013
Tongue
English
Weight
315 KB
Volume
37
Category
Article
ISSN
0253-6269

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## Abstract New 2‐(aminomethyl)‐5‐(hydroxymethyl)pyrrolidine‐3,4‐diol derivatives were synthesized from (5__S__)‐5‐[(trityloxy)methyl]pyrrolidin‐2‐one (**6**) (__Schemesβ€…1__ and __2__) and their inhibitory activities toward 25 glycosidases assayed (__Table__). The influence of the configuration of