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Synthesis and Phosphodiesterase 5 Inhibitory Activity of Novel Pyrido[1,2-e]purin-4(3H)-one Derivatives.

✍ Scribed by Guangxin Xia; Jianfeng Li; Aiming Peng; Shunan Lai; Shujun Zhang; Jingshan Shen; Zhonghua Liu; Xinjian Chen; Ruyun Ji

Publisher
John Wiley and Sons
Year
2005
Weight
22 KB
Volume
36
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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A series of novel 2-(2,4,6-trisubstituted phenyl)-1,3,4-oxadiazolin-5-one derivatives and 3-(2,4,6-trichlorophenyl)pyrazolin-5-one derivatives were synthesized and evaluated for insecticidal activity. It was found that a moderately bulky alkyl group, such as a tert-butyl group, on the heterocyclic r